Negar Fani, PhD and Michael Treadway, PhD, Principal Investigators
Non-invasive brain stimulation to enhance mood and cognition.
Temporal Interference (TI) is an exciting new method for non-invasive stimulation of the brain that is capable of targeting deep brain structures such as the amygdala and striatum. This method can be used to enhance cognitive performance, stress response and emotion regulation. For many years, deep brain stimulation has helped clinicians treat patients with a variety of conditions ranging from depression to Parkinson’s Disease, but the majority of research and clinical applications have used invasive deep brain stimulation, using electrodes implanted in the brain. Using converging electromagnetic waves delivered through electrodes placed on the scalp, Temporal Inference is a non-invasive deep brain stimulation method that has the capability to painlessly activate brain regions that are involved with cognitive and emotional processes, including attention and emotion regulation. The goal of this study is to identify ways in which TI can be used to modulate mood and cognitive processes, such as attention.
What are we studying?
Our objective is to examine whether Temporal Interference applied to brain areas involved with emotion processing, attention and effort-based decision-making can influence mood and task performance, as well as brain response. We will include individuals suffering from psychiatric conditions such as Major Depressive Disorder and Post Traumatic Stress Disorder (PTSD).
What is involved in this study?
Participation in our study will consist of sessions in which you will receive Temporal Interference brain stimulation. We will also record brain responses through the scalp with electroencephalography (EEG) to examine changes related to the brain stimulation. The sessions will last approximately 2 to 4 hours while you complete EEG, stimulation and a series of questionnaires and computer-based tasks.
Who is eligible?
We are currently looking for right-handed adults between the ages of 18 and 50 years of age who are not taking medications that may increase risk of seizure and who have no family history or personal history of seizures. If you are interested, please complete this survey https://redcap.emory.edu/surveys/?s=TRT4CL8H398DEY7R and a team member will contact you if you may be eligible.
