Negar Fani, PhD, Principal Investigator
Non-invasive brain stimulation to enhance mood and cognition.
Temporal Interference (TI) is an exciting new method for non-invasive stimulation of the brain that is capable of targeting deep brain structures such as the amygdala and striatum. These brain regions play key roles in anxiety, motivation and attention. For many years, deep brain stimulation (which uses electrodes implanted via surgery) has been the only choice to affect the function of these regions. Deep brain stimulation has provided relief for variety of conditions ranging from depression to Parkinson’s Disease, but surgery is not an option for many people. Increasingly, studies show that temporal interference deep brain stimulation is capable of similar results, including our own research. Using converging electromagnetic waves delivered through electrodes placed on the scalp, Temporal Inference may painlessly activate or inhibit deep brain regions involved with cognitive and emotional processes. The goal of this study is to use TI stimulation to the amygdala and striatum to reduce anxiety and enhance positive mood and attention.
What are we studying?
Our objective is to examine whether Temporal Interference applied to brain areas involved with anxiety, attention and reward processes may change brain responses, mood and behavior. We will include individuals suffering from psychiatric conditions such as Major Depressive Disorder and Post Traumatic Stress Disorder (PTSD).
What is involved in this study?
Participation in our study will consist of sessions in which you will receive Temporal Interference brain stimulation. We will also record brain responses through the scalp with electroencephalography (EEG) to examine changes related to the brain stimulation. The sessions will last approximately 2 to 4 hours while you complete EEG, stimulation and a series of questionnaires and computer-based tasks.
Who is eligible?
We are currently looking for adults between the ages of 18 and 65 with no history of seizures. If you are interested, please complete this survey https://redcap.emory.edu/surveys/?s=4RXDN4PDPFLCHAA7 and a team member will contact you if you may be eligible.
